Glycolist january-march 2009


very comprehensive:
Tumor suppressors and cell metabolism: a recipe for cancer growth
Russell G. Jones and Craig B. Thompson
Genes Dev. 2009;23 537-548

Mitochondrial Uncoupling and the Warburg Effect: Molecular Basis for the Reprogramming of Cancer Cell Metabolism
Ismael Samudio, Michael Fiegl, and Michael Andreeff
Cancer Res 2009;69 2163-2166

The molecular determinants of de novo nucleotide biosynthesis in cancer cells
Pages 32-37
Xuemei Tong, Fangping Zhao, Craig B Thompson


Oncogenic B-RAF Negatively Regulates the Tumor Suppressor LKB1 to Promote Melanoma Cell Proliferation
B. Zheng, J.H. Jeong, J.M. Asara, Y.-Y. Yuan, S.R. Granter, L. Chin, and L.C. Cantley

mTOR Complex 2 Is Required for the Development of Prostate Cancer Induced by Pten Loss in Mice
D.A. Guertin, D.M. Stevens, M. Saitoh, S. Kinkel, K. Crosby, J.-H. Sheen, D.J. Mullholland, M.A. Magnuson, H. Wu, and D.M. Sabatini

c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism
Ping Gao, Irina Tchernyshyov2, Tsung-Cheng Chang3, Yun-Sil Lee3, Kayoko Kita11, Takafumi Ochi11, Karen I. Zeller1, Angelo M. De Marzo6,7,8, Jennifer E. Van Eyk2,9, Joshua T. Mendell3,4,5 & Chi V. Dang

Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction.
Wise DR, DeBerardinis RJ, Mancuso A, Sayed N, Zhang XY, Pfeiffer HK, Nissim I, Daikhin E, Yudkoff M, McMahon SB, Thompson CB.

ULK1-ATG13-FIP200 complex mediates mTOR signaling and is essential for autophagy
Ian G. Ganley, Du H. Lam, Junru Wang, Xiaojun Ding, She Chen, and Xuejun Jiang
J. Biol. Chem. published 3 March 2009, 10.1074/jbc.M900573200

Autophagy Provides Nutrients but Can Lead to Chop-dependent Induction of Bim to Sensitize Growth Factor–deprived Cells to Apoptosis
Brian J. Altman, Jessica A. Wofford, Yuxing Zhao, Jonathan L. Coloff, Emily C. Ferguson, Heather L. Wieman, Amanda E. Day, Olga Ilkayeva, and Jeffrey C. Rathmell

Bidirectional Transport of Amino Acids Regulates mTOR and Autophagy
P. Nicklin, P. Bergman, B. Zhang, E. Triantafellow, H. Wang, B. Nyfeler, H. Yang, M. Hild, C. Kung, C. Wilson, V.E. Myer, J.P. MacKeigan, J.A. Porter, Y.K. Wang, L.C. Cantley, P.M. Finan, and L.O. Murphy

PLIC proteins or ubiquilins regulate autophagy-dependent cell survival during nutrient starvation
Elsa-Noah N’Diaye, Kimberly K Kajihara, Ivy Hsieh, Hiroshi Morisaki, Jayanta Debnath & Eric J Brown

The pivotal role of c-Jun NH2-terminal kinase-mediated Beclin 1 expression during anticancer agents-induced autophagy in cancer cells
D-D Li, L-L Wang, R Deng, J Tang, Y Shen, J-F Guo, Y Wang, L-P Xia, G-K Feng, Q Q Liu, W-L Huang, Y-X Zeng & X-F Zhu

PARP-1 is involved in autophagy induced by DNA damage
José Antonio Muñoz-Gámez, José Manuel Rodríguez-Vargas, Rosa Quiles-Pérez, Rocío Aguilar-Quesada, David Martín-Oliva, Gilbert de Murcia, Josiane Menissier de Murcia, Antonio Almendros, Mariano Ruiz de Almodóvar and F. Javier Oliver

Silencing of Elongation Factor-2 Kinase Potentiates the Effect of 2-Deoxy-D-Glucose against Human Glioma Cells through Blunting of Autophagy
Hao Wu, Hua Zhu, David X. Liu, Ting-Kuang Niu, Xingcong Ren, Rajesh Patel, William N. Hait, and Jin-Ming Yang
Cancer Res 2009;69 2453-2460

The Warburg Effect Suppresses Oxidative Stress Induced Apoptosis in a Yeast Model for Cancer
Christoph Ruckenstuhl et al.

Inhibition of glycolysis modulates prednisolone resistance in acute lymphoblastic leukemia cells
Esther Hulleman, Karin M. Kazemier, Amy Holleman, David J. VanderWeele, Charles M. Rudin, Mathilde J. C. Broekhuis, William E. Evans, Rob Pieters, and Monique L. Den Boer
Blood 2009;113 2014-2021

Transketolase-like protein 1 (TKTL1) is required for rapid cell growth and full viability of human tumor cells
Xiaojun Xu 1, Axel zur Hausen 2, Johannes F. Coy 3, Martin Löchelt

Chemical hypoxia-induced glucose transporter-4 translocation in neonatal rat cardiomyocytes.
Guan F, Yu B, Qi GX, Hu J, Zeng DY, Luo J.

Tumours with PI3K activation are resistant to dietary restriction
Nada Y. Kalaany and David M. Sabatini

An ATP-competitive mTOR inhibitor reveals rapamycin-insensitive functions of mTORC1
Carson C. Thoreen, Seong A. Kang, Jae Won Chang, Qingsong Liu, Jianming Zhang, Yi Gao, Laurie J. Reichling, Taebo Sim, David M. Sabatini, and Nathanael S. Gray

Rapamycin induces transactivation of the EGFR and increases cell survival
D Chaturvedi, X Gao, M S Cohen, J Taunton & T B Patel

AMP-activated protein kinase is involved in neural stem cell growth suppression and cell cycle arrest by aicar and glucose deprivation by down-regulating phospho-retinoblastoma protein and cyclin D
Yi Zang, Li-Fang Yu, Fa-Jun Nan, Lin-Yin Feng, and Jia Li
J. Biol. Chem. published 14 January 2009, 10.1074/jbc.M806887200

Uncoupling of the LKB1-AMPKα Energy Sensor Pathway by Growth Factors and Oncogenic BRAFV600E
Rosaura Esteve-Puig, Francesc Canals2, Núria Colomé2, Glenn Merlino3, Juan Ángel Recio

Expression of LKB1 tumor suppressor in non-small cell lung cancer determines sensitivity to 2-deoxyglucose
Inge, L. J., Coon, K. D., Smith, M. A., Bremner, R. M.

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