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mTOR, cancer and starvation
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KICSTOR recruits GATOR1 to the lysosome and is necessary for nutrients to regulate mTORC1
Rachel L. Wolfson, Lynne Chantranupong, Gregory A. Wyant, Xin Gu, Jose M. Orozco, Kuang Shen, Kendall J. Condon, Sabrina Petri, Jibril Kedir, Sonia M. Scaria, Monther Abu-Remaileh, Wayne N. Frankel & David M. Sabatini
http://www.nature.com/nature/journal/vaop/ncurrent/full/nature21423.html
SZT2 dictates GATOR control of mTORC1 signalling
Min Peng, Na Yin & Ming O. Li
http://www.nature.com/nature/journal/vaop/ncurrent/full/nature21378.html
Pharmacologic Targeting of S6K1 in PTEN-Deficient Neoplasia
Hongqi Liu, Xizhi Feng, Kelli N. Ennis, Catherine A. Behrmann, Pranjal Sarma, Tony T. Jiang, Satoshi Kofuji, Liang Niu, Yiwen Stratton, Hala Elnakat Thomas, Sang-Oh Yoon, Atsuo T. Sasaki, David R. Plas
http://www.cell.com/cell-reports/fulltext/S2211-1247(17)30203-6
EPRS is a critical mTORC1–S6K1 effector that influences adiposity in mice
Abul Arif, Fulvia Terenzi, Alka A. Potdar, Jie Jia, Jessica Sacks, Arnab China, Dalia Halawani, Kommireddy Vasu, Xiaoxia Li, J. Mark Brown, Jie Chen, Sara C. Kozma, George Thomas & Paul L. Fox
http://www.nature.com/nature/journal/v542/n7641/full/nature21380.html
Lipid Sensing by mTOR via de novo Synthesis of Phosphatidic Acid
Deepak Menon, Darin Salloum, Elyssa Bernfeld, Elizabeth Gorodetsky, Alla Akselrod, Maria A. Frias, Jessica Sudderth, Pei-Hsuan Chen, Ralph DeBerardinis, and David A. Foster
http://www.jbc.org/content/early/2017/02/21/jbc.M116.772988.abstract
mTORC1 Activity is Required to Maintain Canonical Endocytic Recycling Pathway against Lysosomal Delivery
Kristin Dauner, Walaa Eid, Riya Raghupathy, John Presley, and Xiaohui Zha
http://www.jbc.org/content/early/2017/02/14/jbc.M116.771451.abstract
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Starvation / diet and cancer
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Glucose deprivation induces ATF4-mediated apoptosis through TRAIL death receptors
Raffaella Iurlaro, Franziska Püschel, Clara Lucía León-Annicchiarico, Hazel O’Connor, Seamus J. Martin, Daniel Palou-Gramón, Estefanía Lucendo and Cristina Muñoz-Pinedo
http://mcb.asm.org/content/early/2017/02/23/MCB.00479-16.abstract
Phosphoglycerate Kinase 1 Phosphorylates Beclin1 to Induce Autophagy
Xu Qian, Xinjian Li, Qingsong Cai, Chuanbao Zhang, Qiujing Yu, Yuhui Jiang, Jong-Ho Lee, David Hawke, Yugang Wang, Yan Xia, Yanhua Zheng,Bing-Hua Jiang, David X. Liu, Tao Jiang, Zhimin Lu
http://www.cell.com/molecular-cell/fulltext/S1097-2765(17)30053-9
Cap-proximal nucleotides via differential eIF4E binding and alternative promoter usage mediate translational response to energy stress
Ana Tamarkin-Ben-Harush, Jean-Jacques Vasseur, Françoise Debart, Igor Ulitsky, Rivka Dikstein
https://elifesciences.org/content/6/e21907
Snail reprograms glucose metabolism by repressing phosphofructokinase PFKP allowing cancer cell survival under metabolic stress
Nam Hee Kim, Yong Hoon Cha, Jueun Lee, Seon-Hyeong Lee, Ji Hye Yang, Jun Seop Yun, Eunae Sandra Cho, Xianglan Zhang, Miso Nam, Nami Kim, Young-Su Yuk, So Young Cha, Yoonmi Lee, Joo Kyung Ryu, Sunghyouk Park, Jae-Ho Cheong, Sang Won Kang, Soo-Youl Kim, Geum-Sook Hwang, Jong In Yook and Hyun Sil Kim
http://www.nature.com/articles/ncomms14374
Nutrient deprivation in neuroblastoma cells alters 4-hydroxynonenal-induced stress response
Lars Zimmermann, Rudolf Moldzio, Katarina Vazdar, Christopher Krewenka, and Elena E. Pohl
http://www.impactjournals.com/oncotarget/index.php?journal=oncotarget&page=article&op=view&path%5b%5d=14132
ID2 promotes survival of glioblastoma cells during metabolic stress by regulating mitochondrial function
Zhonghua Zhang, Gilbert J Rahme, Pranam D Chatterjee, Matthew C Havrda and Mark A Israel
http://www.nature.com/cddis/journal/v8/n2/abs/cddis201714a.html
Fasting-mimicking diet and markers/risk factors for aging, diabetes, cancer, and cardiovascular disease
Min Wei , Sebastian Brandhorst, Mahshid Shelehchi, Hamed Mirzaei, Chia Wei Cheng, Julia Budniak, Susan Groshen, Wendy J. Mack, Esra Guen, Stefano Di Biase, Pinchas Cohen, Todd E. Morgan, Tanya Dorff, Kurt Hong, Andreas Michalsen, Alessandro Laviano, Valter D. Longo
http://stm.sciencemag.org/content/9/377/eaai8700
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Glucose metabolism
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Epigenomic reprogramming during pancreatic cancer progression links anabolic glucose metabolism to distant metastasis
Oliver G McDonald, Xin Li, Tyler Saunders, Rakel Tryggvadottir, Samantha J Mentch, Marc O Warmoes, Anna E Word, Alessandro Carrer, Tal H Salz, Sonoko Natsume, Kimberly M Stauffer, Alvin Makohon-Moore, Yi Zhong, Hao Wu, Kathryn E Wellen, Jason W Locasale, Christine A Iacobuzio-Donahue & Andrew P Feinberg
http://www.nature.com/ng/journal/v49/n3/full/ng.3753.html
Nur77 suppresses hepatocellular carcinoma via switching glucose metabolism toward gluconeogenesis through attenuating phosphoenolpyruvate carboxykinase sumoylation
Xue-li Bian, Hang-zi Chen, Peng-bo Yang, Ying-ping Li, Fen-na Zhang, Jia-yuan Zhang, Wei-jia Wang, Wen-xiu Zhao, Sheng Zhang, Qi-tao Chen, Yu Zheng, Xiao-yu Sun, Xiao-min Wang, Kun-Yi Chien & Qiao Wu
http://www.nature.com/articles/ncomms14420?
Predictive value of glucose transporter-1 and glucose transporter-3 for survival of cancer patients: A meta-analysis
Xiu Chen, Peng Lu, Siying Zhou, Lei Zhang, Jian-hua Zhao, and Jin-hai Tang
http://www.impactjournals.com/oncotarget/index.php?journal=oncotarget&page=article&op=view&path%5b%5d=14570
O-GlcNAcylation of STAT5 controls tyrosine phosphorylation and oncogenic transcription in STAT5-dependent malignancies.
P Freund, M A Kerenyi, M Hager, T Wagner, B Wingelhofer, H T T Pham, M Elabd, X Han, P Valent, F Gouilleux, V Sexl, O H Krämer, B Groner, R Moriggl.
http://www.nature.com/leu/journal/vaop/ncurrent/full/leu20174a.html
GLUT-1 overexpression as an unfavorable prognostic biomarker in patients with colorectal cancer
Jing Yang, Jing Wen, Tian Tian, Zhongsheng Lu, Yao Wang, Zikai Wang, Xiangdong Wang, and Yunsheng Yang
http://www.impactjournals.com/oncotarget/index.php?journal=oncotarget&page=article&op=view&path%5b%5d=14352
LKB1 inhibits HPV-associated cancer progression by targeting cellular metabolism
Q Zeng, J Chen, Y Li, K D Werle, R-X Zhao, C-S Quan, Y-S Wang, Y-X Zhai, J-W Wang, M Youssef, R Cui, J Liang, N Genovese, L T Chow, Y-L Li and Z-X Xu
http://www.nature.com/onc/journal/v36/n9/abs/onc2016290a.html
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Amino acid metabolism
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Head and Neck Squamous Cell Carcinoma Metabolism draws on Glutaminolysis, and Stemness is Specifically Regulated by Glutaminolysis via Aldehyde Dehydrogenase
Pachiyappan Kamarajan, Thekkelnaycke M. Rajendiran, Jason Kinchen, Mercedes Bermúdez, Theodora Danciu, and Yvonne Lorraine Kapila
http://pubs.acs.org/doi/abs/10.1021/acs.jproteome.6b00936
Haploinsufficiency of SIRT1 Enhances Glutamine Metabolism and Promotes Cancer Development
Natalie S.X. Ren, Ming Ji, Erik J. Tokar, Evan L. Busch, Xiaojiang Xu, DeAsia Lewis, Xiangchun Li, Aiwen Jin, Yanping Zhang, William K.K. Wu, Weichun Huang, Leping Li, David C. Fargo, Temitope O. Keku, Robert S. Sandler, Xiaoling Li
http://www.cell.com/current-biology/fulltext/S0960-9822(16)31529-9
A Relay Pathway between Arginine and Tryptophan Metabolism Confers Immunosuppressive Properties on Dendritic Cells
Giada Mondanelli, Roberta Bianchi, Maria Teresa Pallotta, Ciriana Orabona, Elisa Albini, Alberta Iacono, Maria Laura Belladonna, Carmine Vacca, Francesca Fallarino, Antonio Macchiarulo, Stefano Ugel, Vincenzo Bronte, Federica Gevi, Lello Zolla, Auke Verhaar, Maikel Peppelenbosch, Emilia Maria Cristina Mazza, Silvio Bicciato, Yasmina Laouar, Laura Santambrogio, Paolo Puccetti, Claudia Volpi, Ursula Grohmann
http://www.cell.com/immunity/fulltext/S1074-7613(17)30027-4
ASS1 is a Metabolic Regulator of Colorectal Cancer Pathogenicity
Leslie A. Bateman, Wan-Min Ku, Martin J Heslin, Carlo M Contreras, Christine F. Skibola, and Daniel K. Nomura
http://pubs.acs.org/doi/abs/10.1021/acschembio.6b01158
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Lipids
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Prevention of Dietary-Fat-Fueled Ketogenesis Attenuates BRAF V600E Tumor Growth
Siyuan Xia, Ruiting Lin, Lingtao Jin, Liang Zhao, Hee-Bum Kang, Yaozhu Pan, Shuangping Liu, Guoqing Qian, Zhiyu Qian, Evmorfia Konstantakou, Baotong Zhang, Jin-Tang Dong, Young Rock Chung, Omar Abdel-Wahab, Taha Merghoub, Lu Zhou, Ragini R. Kudchadkar, David H. Lawson, Hanna J. Khoury, Fadlo R. Khuri, Lawrence H. Boise, Sagar Lonial, Benjamin H. Lee, Brian P. Pollack, Jack L. Arbiser, Jun Fan, Qun-Ying Lei, Jing Chen
http://www.cell.com/cell-metabolism/fulltext/S1550-4131(16)30643-X
The microRNA-182-PDK4 axis regulates lung tumorigenesis by modulating pyruvate dehydrogenase and lipogenesis
G Li, M Li, J Hu, R Lei, H Xiong, H Ji, H Yin, Q Wei and G Hu
http://www.nature.com/onc/journal/v36/n7/abs/onc2016265a.html
Survival of tissue-resident memory T cells requires exogenous lipid uptake and metabolism
Youdong Pan, Tian Tian, Chang Ook Park, Serena Y. Lofftus, Shenglin Mei, Xing Liu, Chi Luo, John T. O’Malley, Ahmed Gehad, Jessica E. Teague, Sherrie J. Divito, Robert Fuhlbrigge, Pere Puigserver, James G. Krueger, Gökhan S. Hotamisligil, Rachael A. Clark & Thomas S. Kupper
http://www.nature.com/nature/journal/vaop/ncurrent/full/nature21379.html
Fatty acid synthase inhibits the O-GlcNAcase during oxidative stress
Jennifer A. Groves, Austin O. Maduka, Robert N. O’Meally, Robert N. Cole, and Natasha E. Zachara
http://www.jbc.org/content/early/2017/02/23/jbc.M116.760785.abstract
Fatty acid synthase regulates estrogen receptor-α signaling in breast cancer cells
J A Menendez and R Lupu
http://www.nature.com/oncsis/journal/v6/n2/abs/oncsis20174a.html
Multi-level suppression of receptor-PI3K-mTORC1 by fatty acid synthase inhibitors is crucial for their efficacy against ovarian cancer cells
Renate Wagner, Gerald Stübiger, Daniel Veigel, Michael Wuczkowski, Peter Lanzerstorfer, Julian Weghuber, Emmanouil Karteris, Karin Nowikovsky, Nastasia Wilfinger-Lutz, Christian F. Singer, Ramón Colomer, Bellinda Benhamú, María Luz López-Rodríguez, Peter Valent, and Thomas W. Grunt
http://www.impactjournals.com/oncotarget/index.php?journal=oncotarget&page=article&op=view&path%5b%5d=14591
Adiposity and cancer at major anatomical sites: umbrella review of the literature
Maria Kyrgiou, Ilkka Kalliala, Georgios Markozannes, Marc J Gunter, Evangelos Paraskevaidis, Hani Gabra, Pierre Martin-Hirsch, Konstantinos K Tsilidis
http://www.bmj.com/content/356/bmj.j477
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Hypoxia and HIFs
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The mTOR and PP2A Pathways Regulate PHD2 Phosphorylation to Fine-Tune HIF1α Levels and Colorectal Cancer Cell Survival under Hypoxia
Giusy Di Conza, Sarah Trusso Cafarello, Stefan Loroch, Daniela Mennerich, Sofie Deschoemaeker, Mario Di Matteo, Manuel Ehling, Kris Gevaert, Hans Prenen, Rene Peiman Zahedi, Albert Sickmann, Thomas Kietzmann, Fabiola Moretti, Massimiliano Mazzone
http://www.cell.com/cell-reports/fulltext/S2211-1247(17)30108-0
Selective Reversible Inhibition of Autophagy in Hypoxic Breast Cancer Cells Promotes Pulmonary Metastasis
Christopher M. Dower, Neema Bhat, Edward W. Wang, and Hong-Gang Wang
http://cancerres.aacrjournals.org/content/77/3/646.abstract?etoc
Epithelial Hypoxia-Inducible Factor 2α Facilitates the Progression of Colon Tumors through Recruiting Neutrophils
Daniel Triner, Xiang Xue, Andrew J. Schwartz, Inkyung Jung, Justin A. Colacino, and Yatrik M. Shah
http://mcb.asm.org/content/37/5/e00481-16.abstract?etoc
Mitochondrial deficiency impairs hypoxic induction of HIF-1 transcriptional activity and retards tumor growth
Masaru Koido, Naomi Haga, Aki Furuno, Satomi Tsukahara, Junko Sakurai, Yuri Tani, Shigeo Sato, and Akihiro Tomida
http://www.impactjournals.com/oncotarget/index.php?journal=oncotarget&page=article&op=view&path%5b%5d=14415
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2-HG and L-2HG
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2-Hydroxyglutarate produced by neomorphic IDH mutations suppresses homologous recombination and induces PARP inhibitor sensitivity
Parker L. Sulkowski , Christopher D. Corso, Nathaniel D. Robinson, Susan E. Scanlon, Karin R. Purshouse, Hanwen Bai, Yanfeng Liu, Ranjini K. Sundaram, Denise C. Hegan, Nathan R. Fons, Gregory A. Breuer, Yuanbin Song, Ketu Mishra-Gorur, Henk M. De Feyter, Robin A. de Graaf, Yulia V. Surovtseva, Maureen Kachman, Stephanie Halene, Murat Günel, Peter M. Glazer, Ranjit S. Bindra
http://stm.sciencemag.org/content/9/375/eaal2463
Drosophila larvae synthesize the putative oncometabolite L-2-hydroxyglutarate during normal developmental growth
Hongde Li, Geetanjali Chawla, Alexander J. Hurlburt, Maria C. Sterrett, Olga Zaslaver, James Cox, Jonathan A. Karty, Adam P. Rosebrock, Amy A. Caudy, and Jason M. Tennessen
http://www.pnas.org/content/114/6/1353.full
Glioblastoma Therapy Can Be Augmented by Targeting IDH1-Mediated NADPH Biosynthesis
Daniel R. Wahl, Joseph Dresser, Kari Wilder-Romans, Joshua D. Parsels, Shuang G. Zhao, Mary Davis, Lili Zhao, Maureen Kachman, Stefanie Wernisch, Charles F. Burant, Meredith A. Morgan, Felix Y. Feng, CoreySpeers, Costas A. Lyssiotis, and Theodore S. Lawrence
http://cancerres.aacrjournals.org/content/77/4/960.abstract?etoc
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Drugs
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Discovery and pharmacological characterization of succinate receptor (SUCNR1/GPR91) agonists
Pierre Geubelle, Julie Gilissen, Sébastien Dilly, Laurence Poma, Nadine Dupuis, Céline Laschet, Dayana Abboud, Asuka Inoue, François Jouret, Bernard Pirotte and Julien Hanson
http://onlinelibrary.wiley.com/wol1/doi/10.1111/bph.13738/abstract
Targeting P-glycoprotein function, p53 and energy metabolism: Combination of metformin and 2-deoxyglucose reverses the multidrug resistance of MCF-7/Dox cells to doxorubicin
Chaojun Xue, Changyuan Wang, Yaoting Sun, Qiang Meng, Zhihao Liu, Xiaokui Huo, Pengyuan Sun, Huijun Sun, Xiaodong Ma, Xiaochi Ma, Jinyong Peng, and Kexin Liu
http://www.impactjournals.com/oncotarget/index.php?journal=oncotarget&page=article&op=view&path%5b%5d=14132
Metformin Promotes AMP-activated Protein Kinase-independent Suppression of ΔNp63α and Inhibits Cancer Cell Viability
Yong Yi, Deshi Chen, Juan Ao, Shengnan Sun, Min Wu, Xiaorong Li, Johann Bergholz, Yujun Zhang, and Zhi-Xiong Xiao
http://www.jbc.org/content/early/2017/02/13/jbc.M116.769141.abstract
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Miscellaneous, including immunometabolism
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Mathematical modeling links Wnt signaling to emergent patterns of metabolism in colon cancer
Mary Lee, George T Chen, Eric Puttock, Kehui Wang, Robert A Edwards, Marian L Waterman, John Lowengrub
http://msb.embopress.org/content/13/2/912
Spatiotemporal Analysis of a Glycolytic Activity Gradient Linked to Mouse Embryo Mesoderm Development
Vinay Bulusu, Nicole Prior, Marteinn T. Snaebjornsson, Andreas Kuehne, Katharina F. Sonnen, Jana Kress, Frank Stein, Carsten Schultz, Uwe Sauer, Alexander Aulehla
http://www.cell.com/developmental-cell/fulltext/S1534-5807(17)30042-4
A Gradient of Glycolytic Activity Coordinates FGF and Wnt Signaling during Elongation of the Body Axis in Amniote Embryos
Masayuki Oginuma, Philippe Moncuquet, Fengzhu Xiong, Edward Karoly, Jérome Chal, Karine Guevorkian, Olivier Pourquié
http://www.cell.com/developmental-cell/fulltext/S1534-5807(17)30070-9
A-to-I RNA Editing Up-regulates Human Dihydrofolate Reductase in Breast Cancer
Masataka Nakano, Tatsuki Fukami, Saki Gotoh, and Miki Nakajima
http://www.jbc.org/content/early/2017/02/10/jbc.M117.775684.abstract
The Mitochondrial Rhomboid Protease PARL Is Regulated by PDK2 to Integrate Mitochondrial Quality Control and Metabolism
Guang Shi, G. Angus McQuibban
http://www.cell.com/cell-reports/fulltext/S2211-1247(17)30066-9
Selective in vivo metabolic cell-labeling-mediated cancer targeting
Hua Wang, Ruibo Wang, Kaimin Cai, Hua He, Yang Liu, Jonathan Yen, Zhiyu Wang, Ming Xu, Yiwen Sun,Xin Zhou, Qian Yin, Li Tang, Iwona T Dobrucki,Lawrence W Dobrucki, Eric J Chaney, Stephen A Boppart, Timothy M Fan, Stéphane Lezmi, Xuesi Chen, Lichen Yin & Jianjun Cheng
http://www.nature.com/nchembio/journal/vaop/ncurrent/full/nchembio.2297.html
A UBE2O-AMPKα2 Axis that Promotes Tumor Initiation and Progression Offers Opportunities for Therapy
Isabelle K. Vila, Yixin Yao, Goeun Kim, Weiya Xia, Hyejin Kim, Sun-Joong Kim, Mi-Kyung Park, James P. Hwang, Enrique González-Billalabeitia, Mien-Chie Hung, Su Jung Song, Min Sup Song
http://www.cell.com/cancer-cell/fulltext/S1535-6108(17)30003-X
Metabolic gatekeeper function of B-lymphoid transcription factors
Lai N. Chan, Zhengshan Chen, Daniel Braas, Jae-Woong Lee, Gang Xiao, Huimin Geng, Kadriye Nehir Cosgun, Christian Hurtz, Seyedmehdi Shojaee, Valeria Cazzaniga, Hilde Schjerven, Thomas Ernst, Andreas Hochhaus, Steven M. Kornblau, Marina Konopleva, Miles A. Pufall, Giovanni Cazzaniga, Grace J. Liu, Thomas A. Milne, H. Phillip Koeffler, Theodora S. Ross, Isidro Sánchez-García, Arndt Borkhardt, Keith R. Yamamoto, Ross A. Dickins, Thomas G. Graeber & Markus Müschen
http://www.nature.com/nature/journal/v542/n7642/full/nature21076.html
A Relay Pathway between Arginine and Tryptophan Metabolism Confers Immunosuppressive Properties on Dendritic Cells
Giada Mondanelli, Roberta Bianchi, Maria Teresa Pallotta, Ciriana Orabona, Elisa Albini, Alberta Iacono, Maria Laura Belladonna, Carmine Vacca, Francesca Fallarino, Antonio Macchiarulo, Stefano Ugel, Vincenzo Bronte, Federica Gevi, Lello Zolla, Auke Verhaar, Maikel Peppelenbosch, Emilia Maria Cristina Mazza, Silvio Bicciato, Yasmina Laouar, Laura Santambrogio, Paolo Puccetti, Claudia Volpi, Ursula Grohmann
http://www.cell.com/immunity/fulltext/S1074-7613(17)30027-4
Serine Is an Essential Metabolite for Effector T Cell Expansion
Eric H. Ma, Glenn Bantug, Takla Griss, Stephanie Condotta, Radia M. Johnson, Bozena Samborska, Nello Mainolfi, Vipin Suri, Hannah Guak, Maria L. Balmer, Mark J. Verway, Thomas C. Raissi, Harmony Tsui, Giselle Boukhaled, Sofia Henriques da Costa, Christian Frezza, Connie M. Krawczyk, Adam Friedman, Mark Manfredi, Martin J. Richer, Christoph Hess, Russell G. Jones
http://www.cell.com/cell-metabolism/fulltext/S1550-4131(16)30644-1
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Reviews
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Understanding the Intersections between Metabolism and Cancer Biology
Matthew G. Vander HeidenCorrespondence information about the author Matthew G. Vander HeidenEmail the author Matthew G. Vander Heiden,
Ralph J. DeBerardinisCorrespondence information about the author Ralph J. DeBerardinis
http://www.cell.com/cell/fulltext/S0092-8674(16)31755-X
Focus: Metabolism: Hypoxia‐inducible factors: coupling glucose metabolism and redox regulation with induction of the breast cancer stem cell phenotype
Gregg L Semenza
http://EMBOJ.embopress.org/content/36/3/252?etoc
Mitochondria, cholesterol and cancer cell metabolism
Vicent Ribas, Carmen García-Ruiz and José C. Fernández-Checa
http://clintransmed.springeropen.com/articles/10.1186/s40169-016-0106-5
The Typical Metabolic Modifiers Conferring Improvement in Cancer Resistance
Wen Tan, Zhangfeng Zhong, Shengpeng Wang, Hui Liu, Hua Yu, Rui Tan, Xiaodong Hu, Tingrui Pan and Yitao Wang
http://benthamscience.com/journals/current-medicinal-chemistry/article/149744/
Assessing Tumor Oxygenation for Predicting Outcome in Radiation Oncology: A Review of Studies Correlating Tumor Hypoxic Status and Outcome in the Preclinical and Clinical Settings
Florence Colliez, Bernard Gallez, and Bénédicte F. Jordan
http://journal.frontiersin.org/article/10.3389/fonc.2017.00010/full
Metabolic enzymes: key modulators of functionality in cancer stem-like cells
Bo-Wen Dong, Guang-Ming Qin, Yan Luo, and Jian-Shan Mao
http://www.impactjournals.com/oncotarget/index.php?journal=oncotarget&page=article&op=view&path%5B%5D=14041
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Comments
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S-2HG is an immunometabolite that shapes the T-cell response
Rob A Cairns and Tak W Mak
http://www.nature.com/cdd/journal/v24/n2/full/cdd2016149a.html
An Oncogenic Role for the Ubiquitin Ligase UBE2O by Targeting AMPK-α2 for Degradation
D. Grahame Hardie
http://www.cell.com/cancer-cell/fulltext/S1535-6108(17)30010-7
Breaking Down Neighbors to Fuel Tumorigenesis
John Vaughen, Tatsushi Igaki
http://www.cell.com/developmental-cell/fulltext/S1534-5807(17)30038-2
Metformin: a metabolic modulator
Federico Pietrocola, and Guido Kroemer
http://www.impactjournals.com/oncotarget/index.php?journal=oncotarget&page=article&op=view&path%5B%5D=14794
Lipid Metabolism Fuels Cancer’s Spread
Zhuo Li, Yibin Kang
http://www.cell.com/cell-metabolism/fulltext/S1550-4131(17)30053-0
Webinar: Deciphering cancer: The intersection of epigenetics, metabolism, and tumorigenesis
Kathryn E. Wellen, Jason Locasale
http://www.sciencemag.org/custom-publishing/webinars/deciphering-cancer-intersection-epigenetics-metabolism-and-tumorigenesis
Pancreatic Tumors Exhibit Enhanced Extracellular Protein Catabolism
http://cancerdiscovery.aacrjournals.org/content/7/2/125.2
CD36-Mediated Lipid Metabolism Promotes Metastasis
http://cancerdiscovery.aacrjournals.org/content/7/2/OF12
PROSTATE CANCER: Targeting lipid metabolism
http://www.nature.com/nrurol/journal/vaop/ncurrent/full/nrurol.2017.28.html
Metabolism and Cancer articles 