For a list of publications please check: ResearcherID or search Pubmed (Munoz-Pinedo) for the most recent ones.
• Molecular mechanisms of apoptosis and other forms of cell death induced by glucose deprivation and ischaemia
• Metabolic vulnerabilities in sarcoma
• Tumour microenvironment in sarcoma and lung cancer
Current research topics:
Our lab is interested in the regulation of apoptosis by the glycolytic metabolism, and its aplication to cancer therapy. In particular, we are studying how inhibition of glycolysis triggers apoptosis and autophagy in tumors, and how inhibitors of glucose uptake sensitize tumor cells to chemotherapy. Moreover, we are studying the role of autophagy and endoplasmic reticulum stress in apoptosis and necrosis induced by glucose deprivation and ischemia.
Franziska Püschel, PhD student (predoc)
Miguel Hernández Madrigal, PhD student (predoc)
Francesca Favaro, PhD student (predoc)
Jaime Redondo Pedraza, Technician
Joaquim Moreno Caceres, Project Manager
* If you’re interested in a master, PhD or postdoctoral position in our lab, please contact me.