Munoz-Pinedo lab

This page is maintained by Cristina Muñoz-Pinedo, from the Preclinical and experimental research in thoracic tumors (PrETT) group, part of the Oncobell program at IDIBELL, Barcelona.

For a list of publications please check: ResearcherID or search Pubmed (Munoz-Pinedo) for the most recent ones.

Research lines:

• Characterisation of immune-tumour-stroma connections in thoracic tumours to improve therapeutic approaches.
• Metabolic vulnerabilities of lung cancer and malignant pleural mesothelioma.
• Molecular mechanisms of apoptosis and other forms of cell death induced by metabolic challenges and ischaemia.

Current research topics:

Our lab is interested in the regulation of apoptosis by the glycolytic metabolism, and its aplication to cancer therapy. In particular, we are studying how inhibition of glycolysis triggers apoptosis and autophagy in tumors, and how inhibitors of glucose uptake sensitize tumor cells to chemotherapy. We are also studying the role of endoplasmic reticulum stress and the Integrated Stress Response in apoptosis and necrosis induced by glucose deprivation and ischemia, and in interactions of the tumor cells with the microenvironment and the immune system

Team:

Fedra Luciano Mateo, Postdoctoral researcher

Miguel Hernández Madrigal, PhD student (predoc)

Felipe Jiménez Hernández, PhD student (predoc)

Francesca Favaro, PhD student (predoc)

Joaquim Moreno Caceres, Project Manager

* If you’re interested in a master, PhD or postdoctoral position in our lab, please contact me.