Glucose metabolism
Fructose-1,6-Bisphosphatase 2 Inhibits Sarcoma Progression by Restraining Mitochondrial Biogenesis – Peiwei Huangyang, Fuming Li, Pearl Lee, Itzhak Nissim, Aalim M. Weljie, Anthony Mancuso, Bo Li, Brian Keith, Sam S. Yoon, M. Celeste Simon. https://www.sciencedirect.com/science/article/abs/pii/S1550413119305686
Nuclear Glycogenolysis Modulates Histone Acetylation in Human Non-Small Cell Lung Cancers – Ramon C. Sun, Vikas V. Dukhande, Zhengqiu Zhou, Lyndsay E.A. Young, Shane Emanuelle, Christine Fillmore Brainson, Matthew S. Gentry. https://www.cell.com/cell-metabolism/fulltext/S1550-4131(19)30443-7
An allosteric PGAM1 inhibitor effectively suppresses pancreatic ductal adenocarcinoma – Chen-Lei Wen, Ke Huang, Lu-Lu Jiang, Xiong-Xiong Lu, Yu-Ting Dai, Min-Min Shi, Xiao-Mei Tang, Qing-Bing Wang, Xiao-Dan Zhang, Peng-Hui Wang, Hui-Ti Li, Xiao-Xue Ruan, Li-Wen Wang, Xin-Jing Wang, Qian Wang, Wei Lu, Xiao-Qiang Xiang, Xun Sun, Yan-Hui Xu, Lu-Hua Lai, Qian Zhan, Hong-Wei Li, Cheng-Hong Peng, Jing Chen, Jin-Yan Huang, De-Yong Ye, Sai-Juan Chen, Zhu Chen, Min Li, Yuan Fang, Bai-Yong Shen, and Lu Zhou. https://www.pnas.org/content/116/46/23264.abstract?etoc
PTEN Suppresses Glycolysis by Dephosphorylating and Inhibiting Autophosphorylated PGK1 – Xu Qian, Xinjian Li, Zhumei Shi, Yan Xia, Qingsong Cai, Daqian Xu, Lin Tan, Linyong Du, Yanhua Zheng, Dan Zhao, Chuanbao Zhang, Philip L. Lorenzi, Yongping You, Bing-Hua Jiang, Tao Jiang, Haitao Li, Zhimin Lu. https://www.cell.com/molecular-cell/fulltext/S1097-2765(19)30622-7
Evolved resistance to partial GAPDH inhibition results in loss of the Warburg effect and in a different state of glycolysis – Maria V. Liberti, Annamarie E. Allen, Vijyendra Ramesh, Ziwei Dai, Katherine R. Singleton, Zufeng Guo, Jun O. Liu, Kris C. Wood and Jason W. Locasale. http://www.jbc.org/content/early/2019/11/20/jbc.RA119.010903.abstract
Lactate
Lactate-mediated epigenetic reprogramming regulates formation of human pancreatic cancer-associated fibroblasts – Tushar D Bhagat, Dagny Von Ahrens, Meelad Dawlaty, Yiyu Zou, Joelle Baddour, Abhinav Achreja, Hongyun Zhao, Lifeng Yang, Brijesh Patel, Changsoo Kwak, Gaurav S Choudhary, Shanisha Gordon-Mitchell, Srinivas Aluri, Sanchari Bhattacharyya, Srabani Sahu, Yiting Yu, Matthias Bartenstein, Orsi Giricz, Masako Suzuki, Davendra Sohal, Sonal Gupta, Paola A Guerrero, Surinder Batra, Michael Goggins, Ulrich Steidl, John Greally, Beamon Agarwal, Kith Pradhan, Debabrata Banerjee, Deepak Nagrath, Anirban Maitra, Amit Verma. https://elifesciences.org/articles/50663
Lactic Acidosis Promotes Mitochondrial Biogenesis in Lung Adenocarcinoma Cells, Supporting Proliferation Under Normoxia or Survival Under Hypoxia – Romero-Garcia S, Prado-Garcia H, Valencia-Camargo AD, Alvarez-Pulido A. https://www.frontiersin.org/articles/10.3389/fonc.2019.01053/full
Monocarboxylate transporter 4 (MCT4) is a high affinity transporter capable of exporting lactate in high-lactate microenvironments – Yasna Contreras-Baeza, Pamela Y. Sandoval, Romina Alarcón, Alex Galaz, Francisca Cortés-Molina, Karin Alegría, Felipe Baeza-Lehnert, Robinson Arce-Molina, Anita Guequén, Carlos A Flores, Alejandro San Martín and L. Felipe Barros. http://www.jbc.org/content/early/2019/11/12/jbc.RA119.009093.1.abstract
Cystine / Glutathione
Tumors with TSC mutations are sensitive to CDK7 inhibition through NRF2 and glutathione depletion – Mahsa Zarei, Heng Du, Amin H. Nassar, Rachel E. Yan, Krinio Giannikou, Sneha H. Johnson, Hilaire C. Lam, Elizabeth P. Henske, Yubao Wang, Tinghu Zhang, John Asara and David J. Kwiatkowski. http://jem.rupress.org/content/216/11/2635?etoc
Oncogenic KRAS Sensitizes Lung Adenocarcinoma to GSK-J4–Induced Metabolic and Oxidative Stress – Beom-Jin Hong, Woo-Yong Park, Hwa-Ryeon Kim, Jin Woo Moon, Ho Yeon Lee, Jun Hyung Park, Seon-Kyu Kim, Youngbin Oh, Jae-Seok Roe and Mi-Young Kim. https://cancerres.aacrjournals.org/content/79/22/5849
Glutamine
Glutamine blockade induces divergent metabolic programs to overcome tumor immune evasion – Robert D. Leone, Liang Zhao, Judson M. Englert, Im-Meng Sun, Min-Hee Oh, Im-Hong Sun, Matthew L. Arwood, Ian A. Bettencourt, Chirag H. Patel, Jiayu Wen, Ada Tam, Richard L. Blosser, Eva Prchalova, Jesse Alt, Rana Rais, Barbara S. Slusher, Jonathan D. Powell. https://science.sciencemag.org/content/366/6468/1013
CD9 identifies pancreatic cancer stem cells and modulates glutamine metabolism to fuel tumour growth – Victoria M.-Y. Wang, Rute M. M. Ferreira, Jorge Almagro, Theodore Evan, Nathalie Legrave, May Zaw Thin, David Frith, Joana Carvalho, David J. Barry, Ambrosius P. Snijders, Eleanor Herbert, Emma L. Nye, James I. MacRae and Axel Behrens. https://www.nature.com/articles/s41556-019-0407-1
Lipid metabolism
Essentiality of fatty acid synthase in the 2D to anchorage-independent growth transition in transforming cells – Maria J. Bueno, Veronica Jimenez-Renard, Sara Samino, Jordi Capellades, Alejandra Junza, María Luz López-Rodríguez, Javier Garcia-Carceles, Irene Lopez-Fabuel, Juan P. Bolaños, Navdeep S. Chandel, Oscar Yanes, Ramon Colomer and Miguel Quintela-Fandino. https://www.nature.com/articles/s41467-019-13028-1
A Fatty Acid Oxidation-dependent Metabolic Shift Regulates the Adaptation of BRAF-mutated Melanoma to MAPK Inhibitors – Andrea Aloia, Daniela Müllhaupt, Christophe D. Chabbert, Tanja Eberhart, Stefanie Flückiger-Mangual, Ana Vukolic, Ossia Eichhoff, Anja Irmisch, Leila T. Alexander, Ernesto Scibona, Dennie T. Frederick, Benchun Miao, Tian Tian, Chaoran Cheng, Lawrence N. Kwong, Zhi Wei, Ryan J. Sullivan, Genevieve M. Boland, Meenhard Herlyn, Keith T. Flaherty, Nicola Zamboni, Reinhard Dummer, Gao Zhang, Mitchell P. Levesque, Wilhelm Krek and Werner J. Kovacs. https://clincancerres.aacrjournals.org/content/25/22/6852
Nucleotides
Identification of DHODH as a therapeutic target in small cell lung cancer – Leanne Li , Sheng Rong Ng, Caterina I. Colón, Benjamin J. Drapkin, Peggy P. Hsu, Zhaoqi Li, Christopher S. Nabel, Caroline A. Lewis, Rodrigo Romero, Kim L. Mercer, Arjun Bhutkar, Sarah Phat, David T. Myers, Mandar Deepak Muzumdar, Peter M. K. Westcott, Mary Clare Beytagh, Anna F. Farago, Matthew G. Vander Heiden, Nicholas J. Dyson, Tyler Jacks. https://stm.sciencemag.org/content/11/517/eaaw7852
Loss of thymidine kinase 1 inhibits lung cancer growth and metastatic attributes by reducing GDF15 expression – Parmanand Malvi, Radoslav Janostiak, Arvindhan Nagarajan, Guoping Cai, Narendra Wajapeyee. https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1008439
Deoxycytidine Release from Pancreatic Stellate Cells Promotes Gemcitabine Resistance – Simona Dalin, Mark R. Sullivan, Allison N. Lau, Beatrice Grauman-Boss, Helen S. Mueller, Emanuel Kreidl, Silvia Fenoglio, Alba Luengo, Jacqueline A. Lees, Matthew G. Vander Heiden, Douglas A. Lauffenburger and Michael T. Hemann. https://cancerres.aacrjournals.org/content/79/22/5723
Mitochondria
Lipid signalling drives proteolytic rewiring of mitochondria by YME1L – Thomas MacVicar, Yohsuke Ohba, Hendrik Nolte, Fiona Carola Mayer, Takashi Tatsuta, Hans-Georg Sprenger, Barbara Lindner, Yue Zhao, Jiahui Li, Christiane Bruns, Marcus Krüger, Markus Habich, Jan Riemer, Robin Schwarzer, Manolis Pasparakis, Sinika Henschke, Jens C. Brüning, Nicola Zamboni and Thomas Langer. https://www.nature.com/articles/s41586-019-1738-6
Mitochondrial stress causes neuronal dysfunction via an ATF4-dependent increase in L-2-hydroxyglutarate – Rachel J. Hunt, Lucy Granat, Gregory S. McElroy, Ramya Ranganathan, Navdeep S. Chandel, Joseph M. Bateman. http://jcb.rupress.org/content/early/2019/10/29/jcb.201904148
The ADP/ATP translocase drives mitophagy independent of nucleotide exchange – Atsushi Hoshino, Wei-jia Wang, Shogo Wada, Chris McDermott-Roe, Chantell S. Evans, Bridget Gosis, Michael P. Morley, Komal S. Rathi, Jian Li, Kristina Li, Steven Yang, Meagan J. McManus, Caitlyn Bowman, Prasanth Potluri, Michael Levin, Scott Damrauer, Douglas C. Wallace, Erika L. F. Holzbaur and Zoltan Arany. https://www.nature.com/articles/s41586-019-1667-4
Individual cristae within the same mitochondrion display different membrane potentials and are functionally independent – Dane M Wolf, Mayuko Segawa, Arun Kumar Kondadi, Ruchika Anand, Sean T Bailey, Andreas S Reichert, Alexander M van der Bliek, David B Shackelford, Marc Liesa, Orian S Shirihai. https://www.embopress.org/doi/full/10.15252/embj.2018101056
Mitochondrial Oxidative Phosphorylation Complex Regulates NLRP3 Inflammasome Activation and Predicts Patient Survival in Nasopharyngeal Carcinoma – I-Che Chung, Lih-Chyang Chen, Ngan-Ming Tsang, Wen-Yu Chuang, Tzu-Chieh Liao, Sheng-Ning Yuan, Chun-Nan OuYang, David M Ojcius, Chih-Ching Wu, Yu-Sun Chang. https://www.mcponline.org/content/early/2019/11/13/mcp.RA119.001808.long
A Compendium of Genetic Modifiers of Mitochondrial Dysfunction Reveals Intra-organelle Buffering – Tsz-Leung To, Alejandro M. Cuadros, Hardik Shah, Wendy H.W. Hung, Yang Li, Sharon H. Kim, Daniel H.F. Rubin, Ryan H. Boe, Sneha Rath, John K. Eaton, Federica Piccioni, Amy Goodale, Zohra Kalani, John G. Doench, David E. Root, Stuart L. Schreiber, Scott B. Vafai, Vamsi K. Mootha. https://www.cell.com/cell/fulltext/S0092-8674(19)31182-1
Starvation
Lipid signalling drives proteolytic rewiring of mitochondria by YME1L – Thomas MacVicar, Yohsuke Ohba, Hendrik Nolte, Fiona Carola Mayer, Takashi Tatsuta, Hans-Georg Sprenger, Barbara Lindner, Yue Zhao, Jiahui Li, Christiane Bruns, Marcus Krüger, Markus Habich, Jan Riemer, Robin Schwarzer, Manolis Pasparakis, Sinika Henschke, Jens C. Brüning, Nicola Zamboni and Thomas Langer. https://www.nature.com/articles/s41586-019-1738-6
A MYC–GCN2–eIF2α negative feedback loop limits protein synthesis to prevent MYC-dependent apoptosis in colorectal cancer – Stefanie Schmidt, David Gay, Friedrich Wilhelm Uthe, Sarah Denk, Madelon Paauwe, Niels Matthes, Markus Elmar Diefenbacher, Sheila Bryson, Fiona Clare Warrander, Florian Erhard, Carsten Patrick Ade, Apoorva Baluapuri, Susanne Walz, Rene Jackstadt, Catriona Ford, Georgios Vlachogiannis, Nicola Valeri, Christoph Otto, Christina Schülein-Völk, Katja Maurus, Werner Schmitz, John Raymond Philip Knight, Elmar Wolf, Douglas Strathdee, Almut Schulze, Christoph-Thomas Germer, Andreas Rosenwald, Owen James Sansom, Martin Eilers and Armin Wiegering. https://www.nature.com/articles/s41556-019-0408-0
The ribosomal P-stalk couples amino acid starvation to GCN2 activation in mammalian cells – Heather P Harding, Adriana Ordonez, Felicity Allen, Leopold Parts, Alison J Inglis, Roger L Williams, David Ron. https://elifesciences.org/articles/50149
Asparagine restriction
SLC1A3 contributes to L‐asparaginase resistance in solid tumors – Jianhui Sun, Remco Nagel, Esther A Zaal, Alejandro Piñeiro Ugalde, Ruiqi Han, Natalie Proost, Ji‐Ying Song, Abhijeet Pataskar, Artur Burylo, Haigen Fu, Gerrit J Poelarends, Marieke van de Ven, Olaf van Tellingen, Celia R Berkers, Reuven Agami. https://www.embopress.org/doi/full/10.15252/embj.2019102147
Translational reprogramming marks adaptation to asparagine restriction in cancer – Gaurav Pathria, Joo Sang Lee, Erez Hasnis, Kristofferson Tandoc, David A. Scott, Sachin Verma, Yongmei Feng, Lionel Larue, Avinash D. Sahu, Ivan Topisirovic, Eytan Ruppin and Ze’ev A. Ronai. https://www-nature-com.sire.ub.edu/articles/s41556-019-0415-1
mTOR / AMPK
Phosphatidic acid drives mTORC1 lysosomal translocation in the absence of amino acids – Maria A. Frias, Suman Mukhopadhyay, Elyssa Lehman, Aleksandra Walasek, Matthew Utter, Deepak Menon and David A. Foster. http://www.jbc.org/content/early/2019/11/24/jbc.RA119.010892.abstract
Heat Shock Factor 1 Is a Direct Antagonist of AMP-Activated Protein Kinase – Kuo-Hui Su, Siyuan Dai, Zijian Tang, Meng Xu, Chengkai Dai. https://www.cell.com/molecular-cell/fulltext/S1097-2765(19)30660-4
Autophagic lipid metabolism sustains mTORC1 activity in TSC-deficient neural stem cells – Chenran Wang, Michael A. Haas, Fuchun Yang, Syn Yeo, Takako Okamoto, Song Chen, Jian Wen, Pranjal Sarma, David R. Plas and Jun-Lin Guan. https://www.nature.com/articles/s42255-019-0137-5
Hypoxia
Hypoxia drives glucose transporter 3 expression through HIF-mediated induction of the long non-coding RNA NICI – Victoria Lauer, Steffen Grampp, James Platt, Veronique Lafleur, Olivia Lombardi, Hani Choudhry, Franziska Kranz, Arndt Hartmann, Bernd Wullich, Atsushi Yamamoto, Mathew L Coleman, Peter J Ratcliffe, David R Mole and Johannes Schödel. http://www.jbc.org/content/early/2019/11/05/jbc.RA119.009827.abstract
Absence of HIF1A Leads to Glycogen Accumulation and an Inflammatory Response That Enables Pancreatic Tumor Growth – Marco Maruggi, Fabiana Izidro Layng, Robert Lemos Jr, Guillermina Garcia, Brian P. James, Monica Sevilla, Ferran Soldevilla, Bas J. Baaten, Petrus R. de Jong, Mei Yee Koh and Garth Powis. https://cancerres.aacrjournals.org/content/79/22/5839
Cancer Immunometabolism
Lactate Buildup at the Site of Chronic Inflammation Promotes Disease by Inducing CD4+ T Cell Metabolic Rewiring – Valentina Pucino, Michelangelo Certo, Vinay Bulusu, Danilo Cucchi, Katriona Goldmann, Elena Pontarini, Robert Haas, Joanne Smith, Sarah E. Headland, Kevin Blighe, Massimiliano Ruscica, Frances Humby, Myles J. Lewis, Jurre J. Kamphorst, Michele Bombardieri, Costantino Pitzalis, Claudio Mauro. https://www.cell.com/cell-metabolism/fulltext/S1550-4131(19)30559-5
Cancer-Derived Succinate Promotes Macrophage Polarization and Cancer Metastasis via Succinate Receptor – Jing-Yiing Wu, Tsai-Wang Huang, Yi-Ting Hsieh, Yi-Fu Wang, Chia-Chien Yen, Guan-Lin Lee, Chang-Ching Yeh, Yi-Jen Peng, Ya-Yi Kuo, Hsiu-Ting Wen, Hui-Chen Lin, Cheng-Wen Hsiao, Kenneth K. Wu, Hsing-Jien Kung, Yu-Juei Hsu, Cheng-Chin Kuo. https://www.cell.com/molecular-cell/fulltext/S1097-2765(19)30801-9
Metabolic stress in cancer cells induces immune escape through a PI3K-dependent blockade of IFNγ receptor signaling – Koen A. Marijt, Marjolein Sluijter, Laura Blijleven, Sofie H. Tolmeijer, Ferenc A. Scheeren, Sjoerd H. van der Burg and Thorbald van Hall. https://jitc.biomedcentral.com/articles/10.1186/s40425-019-0627-8
STAT3 Activation-Induced Fatty Acid Oxidation in CD8+ T Effector Cells Is Critical for Obesity-Promoted Breast Tumor Growth – Zhang C, Yue C, Herrmann A, Song J, Egelston C, Wang T, Zhang Z, Li W, Lee H, Aftabizadeh M, Li YJ, Lee PP, Forman S, Somlo G, Chu P, Kruper L, Mortimer J, Hoon DSB, Huang W, Priceman S, Yu H. https://www.sciencedirect.com/science/article/abs/pii/S1550413119306047
Metformin
Metformin Improves Mitochondrial Respiratory Activity through Activation of AMPK – Yu Wang, Hongying An, Ting Liu, Caolitao Qin, Hiromi Sesaki, Shaodong Guo, Sally Radovick, Mehboob Hussain, Akhil Maheshwari, Fredric E. Wondisford, Brian O’Rourke, Ling He. https://www.cell.com/cell-reports/fulltext/S2211-1247(19)31267-7
Metformin prevents liver tumourigenesis by attenuating fibrosis in a transgenic mouse model of hepatocellular carcinoma – Ram C. Shankaraiah, Elisa Callegari, Paola Guerriero, Alessandro Rimessi, Paolo Pinton, Laura Gramantieri, Enrico M. Silini, Silvia Sabbioni and Massimo Negrini. https://www.nature.com/articles/s41388-019-0942-z
Miscellaneous
eIF4A supports an oncogenic translation program in pancreatic ductal adenocarcinoma – Karina Chan, Francis Robert, Christian Oertlin, Dana Kapeller-Libermann, Daina Avizonis, Johana Gutierrez, Abram Handly-Santana, Mikhail Doubrovin, Julia Park, Christina Schoepfer, Brandon Da Silva, Melissa Yao, Faith Gorton, Junwei Shi, Craig J. Thomas, Lauren E. Brown, John A. Porco Jr., Michael Pollak, Ola Larsson, Jerry Pelletier and Iok In Christine Chio. https://www.nature.com/articles/s41467-019-13086-5
Metabolic Profiling Using Stable Isotope Tracing Reveals Distinct Patterns of Glucose Utilization by Physiologically Activated CD8+ T Cells – Eric H. Ma, Mark J. Verway, Radia M. Johnson, Dominic G. Roy, Mya Steadman, Sebastian Hayes, Kelsey S. Williams, Ryan D. Sheldon, Bozena Samborska, Penelope A. Kosinski, Hyeryun Kim, Takla Griss, Brandon Faubert, Stephanie A. Condotta, Connie M. Krawczyk, Ralph J. DeBerardinis, Kelly M. Stewart, Martin J. Richer, Victor Chubukov, Thomas P. Roddy, Russell G. Jones. https://www.cell.com/immunity/fulltext/S1074-7613(19)30374-7
Subcellular metabolic pathway kinetics are revealed by correcting for artifactual post harvest metabolism – Sophie Trefely, Joyce Liu, Katharina Huber, Mary T. Doan, Helen Jiang, Jay Singh, Elianavon Krusenstiern, Anna Bostwick, Peining Xu, Juliane G. Bogner-Strauss, Kathryn E. Wellen, Nathaniel W.Snyder. https://www.sciencedirect.com/science/article/pii/S221287781930907X
Reviews
Nutrient regulation of mTORC1 at a glance – Kendall J. Condon and David M. Sabatini. http://jcs.biologists.org/content/132/21/jcs222570?etoc
Metabolism in the Tumor Microenvironment – Allison N. Lau and Matthew G. Vander Heiden. https://www.annualreviews.org/doi/abs/10.1146/annurev-cancerbio-030419-033333
Lipid Metabolism at the Nexus of Diet and Tumor Microenvironment – Barrie Peck, Almut Schulze. https://www.cell.com/trends/cancer/fulltext/S2405-8033(19)30190-6
Targeting cellular cholesterol for anticancer therapy – Liang Gu, Sourav Taru Saha, Jodie Thomas, Mandeep Kaur. https://febs.onlinelibrary.wiley.com/doi/abs/10.1111/febs.15018
DUBs, Hypoxia, and Cancer – Daniela Mennerich, Kateryna Kubaichuk, Thomas Kietzmann. https://www.cell.com/trends/cancer/fulltext/S2405-8033(19)30182-7
Lactate in the Regulation of Tumor Microenvironment and Therapeutic Approaches – de la Cruz-López KG, Castro-Muñoz LJ, Reyes-Hernández DO, García-Carrancá A, Manzo-Merino J. https://www.frontiersin.org/articles/10.3389/fonc.2019.01143/full
New insights into transcriptional reprogramming during cellular stress – Samu V. Himanen, Lea Sistonen. https://jcs.biologists.org/content/132/21/jcs238402?etoc
Tracking intra‐ and inter‐organelle signaling of mitochondria – Corina T. Madreiter‐Sokolowski, Jeta Ramadani‐Muja, Gabriela Ziomek, Sandra Burgstaller, Helmut Bischof, Zhanat Koshenov, Benjamin Gottschalk, Roland Malli, Wolfgang F. Graier. https://febs.onlinelibrary.wiley.com/doi/full/10.1111/febs.15103
Modular biogenesis of mitochondrial respiratory complexes – Mario H. Barrosa, Gavin P. McStay. https://www.sciencedirect.com/science/article/pii/S1567724919301394
Comments
Running the Light: Nucleotide Metabolism Drives Bypass of Senescence in Cancer – Christopher J. Halbrook, Daniel R. Wahl, Costas A. Lyssiotis. https://www.cell.com/trends/biochemical-sciences/fulltext/S0968-0004(19)30208-7
Metabolic vulnerability in tumours illuminated – Aparna D. Rao, Ralph J. DeBerardinis. https://www.nature.com/articles/d41586-019-03239-3
The Transsulfuration Pathway Makes, the Tumor Takes – Ross Weber, Kıvanç Birsoy. https://www.cell.com/cell-metabolism/fulltext/S1550-4131(19)30565-
Metabolic Stress Triggers Immune Escape by Tumors – Joana B. Nunes, Bart Everts. https://www.cell.com/trends/cancer/fulltext/S2405-8033(19)30184-0
Mitochondrial cristae as insulated transformers of metabolic energy – Michael Schlame. https://www.embopress.org/doi/abs/10.15252/embj.2019103472
Metabolic adaption through regulated proteolysis – Wei Wong. https://stke.sciencemag.org/content/12/608/eaba2257
T Cell Metabolism in a State of Flux – Siva Karthik Varanasi, Shixin Ma, Susan M. Kaech. https://www.cell.com/immunity/fulltext/S1074-7613(19)30456-X
Extra: Christian Frezza’s selections
http://biomed.news/bims-camemi/2019-11-10
http://biomed.news/bims-camemi/2019-11-17
Metabolism and Cancer articles 